A rare PALB2 germline variant causing G2/M cell cycle arrest is associated with isolated myelosarcoma in infancy

BACKGROUND: Isolated myelosarcoma of infancy is a rare presentation of acute myelogenous leukaemia (AML). Because of its rarity and early onset in infancy underlying genetic predisposition is potentially relevant in disease initiation. METHODS AND RESULTS: We report an oncologic emergency in an infa...

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Detalles Bibliográficos
Autores principales: Beer, Angelina, Beck, Ricardo, Schedel, Anne, von Bonin, Malte, Meinel, Jörn, Friedrich, Ulrike Anne, Menzel, Maria, Suttorp, Meinolf, Brenner, Sebastian, Fitze, Guido, Lange, Björn, Knöfler, Ralf, Hauer, Julia, Auer, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Clinical Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457705/
https://www.ncbi.nlm.nih.gov/pubmed/34382369
http://dx.doi.org/10.1002/mgg3.1746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457705/
https://www.ncbi.nlm.nih.gov/pubmed/34382369
http://dx.doi.org/10.1002/mgg3.1746

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