Semi-Synthesis of New 1,2,3-Triazole Derivatives of 9-Bromonoscapine and their Anticancer Activities

Novel 1,2,3-triazole-tethered 9-bromonoscapine derivatives were synthesized by the propargylation of N-nornoscapine followed by Huisgen’s 1,3-dipolar cycloaddition of the terminal alkynes with different azides. Cytotoxicity of the products was studied by MTT assay against the MCF-7 breast cancer cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Hasanpour, Zahra, Salehi, Peyman, Bararjanian, Morteza, Esmaeili, Mohammad-Ali, Alilou, Mostafa, Mohebbi, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457714/
https://www.ncbi.nlm.nih.gov/pubmed/34567181
http://dx.doi.org/10.22037/ijpr.2020.113213.14170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457714/
https://www.ncbi.nlm.nih.gov/pubmed/34567181
http://dx.doi.org/10.22037/ijpr.2020.113213.14170

Ejemplares similares