Studying the Expression Efficiencies of Human Clotting Factor IX Analogs, Rationally-designed for Hyper-glycosylation

Glyco-engineering has attracted lots of interest in studies dealing with the pharmacokinetics of therapeutic proteins. Based on our previous in-silico studies, two sites were selected in the N-terminal gamma-carboxy glutamic acid-rich (Gla) domain of the human clotting factor IX (hFIX) to add new N-...

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Detalles Bibliográficos
Autores principales: Ghasemi, Fahimeh, Khorramizadeh, M.Reza, Karkhane, Ali Asghar, Zomorodipour, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457720/
https://www.ncbi.nlm.nih.gov/pubmed/34567179
http://dx.doi.org/10.22037/ijpr.2020.112027.13503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457720/
https://www.ncbi.nlm.nih.gov/pubmed/34567179
http://dx.doi.org/10.22037/ijpr.2020.112027.13503

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