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Synthesis, Kinetics, Binding Conformations and Structure-activity Relationship of Potent Tyrosinase Inhibitors: Aralkylated 2-aminothiazole-ethyltriazole Hybrids

Considering the diversified pharmacological importance of thiazole and triazole heterocyclic moieties, a unique series of S-aralkylated bi-heterocyclic hybrids, 7a-l, was synthesized in a convergent manner. The structures of newly synthesized compounds were characterized by (1)H-NMR, (13)C-NMR, IR,...

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Detalles Bibliográficos
Autores principales: Sadiq Butt, Abdul Rehman, Abbasi, Muhammad Athar, Rehman, Aziz-ur-, Siddiqui, Sabahat Zahra, Raza, Hussain, Hassan, Mubashir, Shah, Syed Adnan Ali, Seo, Sung-Yum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457735/
https://www.ncbi.nlm.nih.gov/pubmed/34567157
http://dx.doi.org/10.22037/ijpr.2020.15521.13145