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WNT16 is Robustly Increased by Oncostatin M in Mouse Calvarial Osteoblasts and Acts as a Negative Feedback Regulator of Osteoclast Formation Induced by Oncostatin M

BACKGROUND: Bone loss is often observed adjacent to inflammatory processes. The WNT signaling pathways have been implicated as novel regulators of both immune responses and bone metabolism. WNT16 is important for cortical bone mass by inhibiting osteoclast differentiation, and we have here investiga...

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Detalles Bibliográficos
Autores principales: Henning, Petra, Movérare-Skrtic, Sofia, Westerlund, Anna, Chaves de Souza, Pedro Paulo, Floriano-Marcelino, Thais, Nilsson, Karin H, El Shahawy, Maha, Ohlsson, Claes, Lerner, Ulf H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457865/
https://www.ncbi.nlm.nih.gov/pubmed/34566421
http://dx.doi.org/10.2147/JIR.S323435