A robust high-throughput fluorescent polarization assay for the evaluation and screening of SARS-CoV-2 fusion inhibitors

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a serious threat to global health. One attractive antiviral target is the membrane fusion mechanism employed by the virus to gain access to the host cell. Here we report a robust protein-based fluorescent polarization assay, that mimick...

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Detalles Bibliográficos
Autores principales: Yin, Xinjian, Chen, Litong, Yuan, Siwen, Liu, Lan, Gao, Zhizeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457910/
https://www.ncbi.nlm.nih.gov/pubmed/34598089
http://dx.doi.org/10.1016/j.bioorg.2021.105362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457910/
https://www.ncbi.nlm.nih.gov/pubmed/34598089
http://dx.doi.org/10.1016/j.bioorg.2021.105362

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