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A robust high-throughput fluorescent polarization assay for the evaluation and screening of SARS-CoV-2 fusion inhibitors
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a serious threat to global health. One attractive antiviral target is the membrane fusion mechanism employed by the virus to gain access to the host cell. Here we report a robust protein-based fluorescent polarization assay, that mimick...
Autores principales: | Yin, Xinjian, Chen, Litong, Yuan, Siwen, Liu, Lan, Gao, Zhizeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457910/ https://www.ncbi.nlm.nih.gov/pubmed/34598089 http://dx.doi.org/10.1016/j.bioorg.2021.105362 |
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