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MicroRNA-let-7 Targets HMGA2 to Regulate the Proliferation, Migration, and Invasion of Colon Cancer Cell HCT116

OBJECTIVE: To investigate the effect of microRNA-let-7 (miR-let-7) on the proliferation, migration, and invasion of colon cancer cell HCT116 in vitro and its regulatory mechanism on downstream HMGA2. METHODS: It was planned to synthesize miR-let-7 overexpression (mimics) and interference expression...

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Detalles Bibliográficos
Autores principales: Chen, Zheng, Liu, Jiheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457942/
https://www.ncbi.nlm.nih.gov/pubmed/34567205
http://dx.doi.org/10.1155/2021/2134942