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A Prospective Clinical Study on MGMT Protein Expression and the Effect of Gene Promoter Methylation on Sensitivity to Chemotherapeutics in Spinal Glioma

OBJECTIVE: The present study discusses the O6-methylguanine-DNA methyltransferase (MGMT) protein expression of spinal glioma cells and the correlation between the sensitivity of promoter methylation of the MGMT gene to chemotherapy drugs, establishes a prediction method for the sensitivity of chemot...

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Detalles Bibliográficos
Autores principales: Sun, Peng, Fan, Duo-Jiao, Fan, Tao, Li, Xin, Qi, Xue-Ling, Zhao, Xin-Gang, Gai, Qi-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458026/
https://www.ncbi.nlm.nih.gov/pubmed/34566423
http://dx.doi.org/10.2147/JIR.S321790