SimFFPE and FilterFFPE: improving structural variant calling in FFPE samples

BACKGROUND: Artifact chimeric reads are enriched in next-generation sequencing data generated from formalin-fixed paraffin-embedded (FFPE) samples. Previous work indicated that these reads are characterized by erroneous split-read support that is interpreted as evidence of structural variants. Thus,...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Lanying, Dugas, Martin, Sandmann, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458033/
https://www.ncbi.nlm.nih.gov/pubmed/34553214
http://dx.doi.org/10.1093/gigascience/giab065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458033/
https://www.ncbi.nlm.nih.gov/pubmed/34553214
http://dx.doi.org/10.1093/gigascience/giab065

Ejemplares similares