Bacterial O-GlcNAcase genes abundance decreases in ulcerative colitis patients and its administration ameliorates colitis in mice

OBJECTIVE: O-linked N-acetylglucosaminylation (O-GlcNAcylation), controlled by O-GlcNAcase (OGA) and O-GlcNAc transferase (OGT), is an important post-translational modification of eukaryotic proteins and plays an essential role in regulating gut inflammation. Gut microbiota encode various enzymes in...

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Detalles Bibliográficos
Autores principales: He, Xiaolong, Gao, Jie, Peng, Liang, Hu, Tongtong, Wan, Yu, Zhou, Meijuan, Zhen, Peilin, Cao, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Inflammatory Bowel Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458092/
https://www.ncbi.nlm.nih.gov/pubmed/33310751
http://dx.doi.org/10.1136/gutjnl-2020-322468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458092/
https://www.ncbi.nlm.nih.gov/pubmed/33310751
http://dx.doi.org/10.1136/gutjnl-2020-322468

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