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Rad27 and Exo1 function in different excision pathways for mismatch repair in Saccharomyces cerevisiae

Eukaryotic DNA Mismatch Repair (MMR) involves redundant exonuclease 1 (Exo1)-dependent and Exo1-independent pathways, of which the Exo1-independent pathway(s) is not well understood. The exo1Δ440-702 mutation, which deletes the MutS Homolog 2 (Msh2) and MutL Homolog 1 (Mlh1) interacting peptides (SH...

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Detalles Bibliográficos
Autores principales: Calil, Felipe A., Li, Bin-Zhong, Torres, Kendall A., Nguyen, Katarina, Bowen, Nikki, Putnam, Christopher D., Kolodner, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458276/
https://www.ncbi.nlm.nih.gov/pubmed/34552065
http://dx.doi.org/10.1038/s41467-021-25866-z