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ZGRF1 promotes end resection of DNA homologous recombination via forming complex with BRCA1/EXO1

To maintain genomic stability, the mammalian cells has evolved a coordinated response to DNA damage, including activation of DNA repair and cell cycle checkpoint processes. Exonuclease 1 (EXO1)-dependent excision of DNA ends is important for the initiation of homologous recombination (HR) repair of...

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Detalles Bibliográficos
Autores principales: Yan, Shuang, Song, Man, Ping, Jie, Lai, Shu-ting, Cao, Xiao-yu, Bai, Chen-Jun, Xie, Da-Fei, Guan, Hua, Gao, Shan-shan, Zhou, Ping-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458317/
https://www.ncbi.nlm.nih.gov/pubmed/34552057
http://dx.doi.org/10.1038/s41420-021-00633-7