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ZGRF1 promotes end resection of DNA homologous recombination via forming complex with BRCA1/EXO1
To maintain genomic stability, the mammalian cells has evolved a coordinated response to DNA damage, including activation of DNA repair and cell cycle checkpoint processes. Exonuclease 1 (EXO1)-dependent excision of DNA ends is important for the initiation of homologous recombination (HR) repair of...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458317/ https://www.ncbi.nlm.nih.gov/pubmed/34552057 http://dx.doi.org/10.1038/s41420-021-00633-7 |