Structural basis of human PDZD8–Rab7 interaction for the ER-late endosome tethering

The membrane contact sites (MCSs) between the ER and late endosomes (LEs) are essential for the regulation of endosomal protein sorting, dynamics, and motility. PDZD8 is an ER transmembrane protein containing a Synaptotagmin-like Mitochondrial lipid-binding Proteins (SMP) domain. PDZD8 tethers the E...

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Detalles Bibliográficos
Autores principales: Khan, Haider, Chen, Lin, Tan, Lingchen, Im, Young Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458453/
https://www.ncbi.nlm.nih.gov/pubmed/34552186
http://dx.doi.org/10.1038/s41598-021-98419-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458453/
https://www.ncbi.nlm.nih.gov/pubmed/34552186
http://dx.doi.org/10.1038/s41598-021-98419-5

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