Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization

Expression of a few master transcription factors can reprogram the epigenetic landscape and three-dimensional chromatin topology of differentiated cells and achieve pluripotency. During reprogramming, thousands of long-range chromatin contacts are altered, and changes in promoter association with en...

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Detalles Bibliográficos
Autores principales: Sharma, Rajesh, Choi, Kyoung-Jae, Quan, My Diem, Sharma, Sonum, Sankaran, Banumathi, Park, Hyekyung, LaGrone, Anel, Kim, Jean J., MacKenzie, Kevin R., Ferreon, Allan Chris M., Kim, Choel, Ferreon, Josephine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458463/
https://www.ncbi.nlm.nih.gov/pubmed/34552088
http://dx.doi.org/10.1038/s41467-021-25761-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458463/
https://www.ncbi.nlm.nih.gov/pubmed/34552088
http://dx.doi.org/10.1038/s41467-021-25761-7

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