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Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization
Expression of a few master transcription factors can reprogram the epigenetic landscape and three-dimensional chromatin topology of differentiated cells and achieve pluripotency. During reprogramming, thousands of long-range chromatin contacts are altered, and changes in promoter association with en...
Autores principales: | Sharma, Rajesh, Choi, Kyoung-Jae, Quan, My Diem, Sharma, Sonum, Sankaran, Banumathi, Park, Hyekyung, LaGrone, Anel, Kim, Jean J., MacKenzie, Kevin R., Ferreon, Allan Chris M., Kim, Choel, Ferreon, Josephine C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458463/ https://www.ncbi.nlm.nih.gov/pubmed/34552088 http://dx.doi.org/10.1038/s41467-021-25761-7 |
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