A novel lncRNA Discn fine-tunes replication protein A (RPA) availability to promote genomic stability

RPA is a master regulator of DNA metabolism and RPA availability acts as a rate-limiting factor. While numerous studies focused on the post-translational regulations of RPA for its functions, little is known regarding how RPA availability is controlled. Here we identify a novel lncRNA Discn as the g...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Li, Jingzheng, Zhou, Hu, Zhang, Weidao, Gao, Jing, Zheng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458541/
https://www.ncbi.nlm.nih.gov/pubmed/34552092
http://dx.doi.org/10.1038/s41467-021-25827-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458541/
https://www.ncbi.nlm.nih.gov/pubmed/34552092
http://dx.doi.org/10.1038/s41467-021-25827-6

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