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A novel lncRNA Discn fine-tunes replication protein A (RPA) availability to promote genomic stability
RPA is a master regulator of DNA metabolism and RPA availability acts as a rate-limiting factor. While numerous studies focused on the post-translational regulations of RPA for its functions, little is known regarding how RPA availability is controlled. Here we identify a novel lncRNA Discn as the g...
Autores principales: | Wang, Lin, Li, Jingzheng, Zhou, Hu, Zhang, Weidao, Gao, Jing, Zheng, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458541/ https://www.ncbi.nlm.nih.gov/pubmed/34552092 http://dx.doi.org/10.1038/s41467-021-25827-6 |
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