Proliferative diabetic retinopathy transcriptomes reveal angiogenesis, anti-angiogenic therapy escape mechanisms, fibrosis and lymphatic involvement

Proliferative diabetic retinopathy (PDR) is a sight-threatening diabetic complication in urgent need of new therapies. In this study we identify potential molecular mechanisms and target candidates in the pathogenesis of PDR fibrovascular tissue formation. We performed mRNA sequencing of RNA isolate...

Descripción completa

Detalles Bibliográficos
Autores principales: Korhonen, Ani, Gucciardo, Erika, Lehti, Kaisa, Loukovaara, Sirpa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458546/
https://www.ncbi.nlm.nih.gov/pubmed/34552123
http://dx.doi.org/10.1038/s41598-021-97970-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458546/
https://www.ncbi.nlm.nih.gov/pubmed/34552123
http://dx.doi.org/10.1038/s41598-021-97970-5

Ejemplares similares