The Tec Kinase Itk Integrates Naïve T Cell Migration and In Vivo Homeostasis

Naïve T cells (T(N)) constitutively recirculate through secondary lymphatic organs (SLOs), where they scan dendritic cells (DCs) for cognate peptide-loaded major histocompatibility complexes (pMHC). Continuous trafficking between SLOs not only enables rapid clonal selection but also ensures T(N) hom...

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Detalles Bibliográficos
Autores principales: Thelen, Flavian, Wissmann, Stefanie, Ruef, Nora, Stein, Jens V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458560/
https://www.ncbi.nlm.nih.gov/pubmed/34566971
http://dx.doi.org/10.3389/fimmu.2021.716405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458560/
https://www.ncbi.nlm.nih.gov/pubmed/34566971
http://dx.doi.org/10.3389/fimmu.2021.716405

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