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The Tec Kinase Itk Integrates Naïve T Cell Migration and In Vivo Homeostasis

Naïve T cells (T(N)) constitutively recirculate through secondary lymphatic organs (SLOs), where they scan dendritic cells (DCs) for cognate peptide-loaded major histocompatibility complexes (pMHC). Continuous trafficking between SLOs not only enables rapid clonal selection but also ensures T(N) hom...

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Detalles Bibliográficos
Autores principales:	Thelen, Flavian, Wissmann, Stefanie, Ruef, Nora, Stein, Jens V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458560/ https://www.ncbi.nlm.nih.gov/pubmed/34566971 http://dx.doi.org/10.3389/fimmu.2021.716405

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