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The Novel Antioxidant Compound JSH-23 Prevents Osteolysis by Scavenging ROS During Both Osteoclastogenesis and Osteoblastogenesis

Inflammatory osteolysis is a pathological skeletal disease associated with not only the production of inflammatory cytokines but also local oxidative status. Excessive reactive oxygen species (ROS) promote bone resorption by osteoclasts and induce the apoptosis of osteoblasts. In consideration of th...

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Detalles Bibliográficos
Autores principales: Mei, Liangwei, Zheng, Yi, Ma, Teng, Xia, Bing, Gao, Xue, Hao, Yiming, Luo, Zhuojing, Huang, Jinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458573/
https://www.ncbi.nlm.nih.gov/pubmed/34566656
http://dx.doi.org/10.3389/fphar.2021.734774