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Influence of CYP2D6 and CYP3A5 Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Bisoprolol in Hypertensive Chinese Patients

Purpose: This study was performed to investigate the effects of common polymorphisms in CYP2D6 and CYP3A5 on the plasma concentrations and antihypertensive effects of bisoprolol in hypertensive Chinese patients. Methods: One hundred patients with essential hypertension were treated with open-label b...

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Detalles Bibliográficos
Autores principales: Chan, Sze Wa, Chu, Tanya T. W., Ho, Chung Shun, Kong, Alice P. S., Tomlinson, Brian, Zeng, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458697/
https://www.ncbi.nlm.nih.gov/pubmed/34568359
http://dx.doi.org/10.3389/fmed.2021.683498