Influence of CYP2D6 and CYP3A5 Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Bisoprolol in Hypertensive Chinese Patients

Purpose: This study was performed to investigate the effects of common polymorphisms in CYP2D6 and CYP3A5 on the plasma concentrations and antihypertensive effects of bisoprolol in hypertensive Chinese patients. Methods: One hundred patients with essential hypertension were treated with open-label b...

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Bibliographic Details
Main Authors: Chan, Sze Wa, Chu, Tanya T. W., Ho, Chung Shun, Kong, Alice P. S., Tomlinson, Brian, Zeng, Weiwei
Format: Online Article Text
Language:English
Published: Frontiers Media S.A. 2021
Subjects:
Medicine
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458697/
https://www.ncbi.nlm.nih.gov/pubmed/34568359
http://dx.doi.org/10.3389/fmed.2021.683498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458697/
https://www.ncbi.nlm.nih.gov/pubmed/34568359
http://dx.doi.org/10.3389/fmed.2021.683498

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