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Influence of CYP2D6 and CYP3A5 Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Bisoprolol in Hypertensive Chinese Patients
Purpose: This study was performed to investigate the effects of common polymorphisms in CYP2D6 and CYP3A5 on the plasma concentrations and antihypertensive effects of bisoprolol in hypertensive Chinese patients. Methods: One hundred patients with essential hypertension were treated with open-label b...
Autores principales: | Chan, Sze Wa, Chu, Tanya T. W., Ho, Chung Shun, Kong, Alice P. S., Tomlinson, Brian, Zeng, Weiwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458697/ https://www.ncbi.nlm.nih.gov/pubmed/34568359 http://dx.doi.org/10.3389/fmed.2021.683498 |
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