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Complement Factor D as a Strategic Target for Regulating the Alternative Complement Pathway

The complement system is central to first-line defense against invading pathogens. However, excessive complement activation and/or the loss of complement regulation contributes to the development of autoimmune diseases, systemic inflammation, and thrombosis. One of the three pathways of the compleme...

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Detalles Bibliográficos
Autores principales: Barratt, Jonathan, Weitz, Ilene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458797/
https://www.ncbi.nlm.nih.gov/pubmed/34566967
http://dx.doi.org/10.3389/fimmu.2021.712572