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The CSF1R-Microglia Axis Has Protective Host-Specific Roles During Neurotropic Picornavirus Infection

Viral encephalitis is a major cause of morbidity and mortality, but the manifestation of disease varies greatly between individuals even in response to the same virus. Microglia are professional antigen presenting cells that reside in the central nervous system (CNS) parenchyma that are poised to re...

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Detalles Bibliográficos
Autores principales: Sanchez, John Michael S., DePaula-Silva, Ana Beatriz, Doty, Daniel J., Hanak, Tyler J., Truong, Amanda, Libbey, Jane E., Fujinami, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458822/
https://www.ncbi.nlm.nih.gov/pubmed/34566948
http://dx.doi.org/10.3389/fimmu.2021.621090