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Mammary Tumorigenesis and Metabolome in Male Adipose Specific Monocyte Chemotactic Protein-1 Deficient MMTV-PyMT Mice Fed a High-Fat Diet

Male breast cancer, while uncommon, is a highly malignant disease. Monocyte chemotactic protein-1 (MCP-1) is an adipokine; its concentration in adipose tissue is elevated in obesity. This study tested the hypothesis that adipose-derived MCP-1 contributes to male breast cancer. In a 2x2 design, male...

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Detalles Bibliográficos
Autores principales: Yan, Lin, Sundaram, Sneha, Rust, Bret M., Picklo, Matthew J., Bukowski, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458874/
https://www.ncbi.nlm.nih.gov/pubmed/34568008
http://dx.doi.org/10.3389/fonc.2021.667843