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Systematic Evaluation of DNA Sequence Variations on in vivo Transcription Factor Binding Affinity
The majority of the single nucleotide variants (SNVs) identified by genome-wide association studies (GWAS) fall outside of the protein-coding regions. Elucidating the functional implications of these variants has been a major challenge. A possible mechanism for functional non-coding variants is that...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458901/ https://www.ncbi.nlm.nih.gov/pubmed/34567058 http://dx.doi.org/10.3389/fgene.2021.667866 |