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Systematic Evaluation of DNA Sequence Variations on in vivo Transcription Factor Binding Affinity

The majority of the single nucleotide variants (SNVs) identified by genome-wide association studies (GWAS) fall outside of the protein-coding regions. Elucidating the functional implications of these variants has been a major challenge. A possible mechanism for functional non-coding variants is that...

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Detalles Bibliográficos
Autores principales:	Jin, Yutong, Jiang, Jiahui, Wang, Ruixuan, Qin, Zhaohui S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458901/ https://www.ncbi.nlm.nih.gov/pubmed/34567058 http://dx.doi.org/10.3389/fgene.2021.667866

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