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MCL-1 Inhibition Overcomes Anti-apoptotic Adaptation to Targeted Therapies in B-Cell Precursor Acute Lymphoblastic Leukemia

Multiple targeted therapies are currently explored for pediatric and young adult B-cell precursor acute lymphoblastic leukemia (BCP-ALL) treatment. However, this new armamentarium of therapies faces an old problem: choosing the right treatment for each patient. The lack of predictive biomarkers is p...

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Detalles Bibliográficos
Autores principales: Manzano-Muñoz, Albert, Alcon, Clara, Menéndez, Pablo, Ramírez, Manuel, Seyfried, Felix, Debatin, Klaus-Michael, Meyer, Lüder H., Samitier, Josep, Montero, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458912/
https://www.ncbi.nlm.nih.gov/pubmed/34568318
http://dx.doi.org/10.3389/fcell.2021.695225