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MAVS: A Two-Sided CARD Mediating Antiviral Innate Immune Signaling and Regulating Immune Homeostasis

Mitochondrial antiviral signaling protein (MAVS) functions as a “switch” in the immune signal transduction against most RNA viruses. Upon viral infection, MAVS forms prion-like aggregates by receiving the cytosolic RNA sensor retinoic acid-inducible gene I-activated signaling and further activates/s...

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Detalles Bibliográficos
Autores principales: Chen, Yunqiang, Shi, Yuheng, Wu, Jing, Qi, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458965/
https://www.ncbi.nlm.nih.gov/pubmed/34566944
http://dx.doi.org/10.3389/fmicb.2021.744348