Cargando…
MAVS: A Two-Sided CARD Mediating Antiviral Innate Immune Signaling and Regulating Immune Homeostasis
Mitochondrial antiviral signaling protein (MAVS) functions as a “switch” in the immune signal transduction against most RNA viruses. Upon viral infection, MAVS forms prion-like aggregates by receiving the cytosolic RNA sensor retinoic acid-inducible gene I-activated signaling and further activates/s...
Autores principales: | Chen, Yunqiang, Shi, Yuheng, Wu, Jing, Qi, Nan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458965/ https://www.ncbi.nlm.nih.gov/pubmed/34566944 http://dx.doi.org/10.3389/fmicb.2021.744348 |
Ejemplares similares
-
An autoinhibitory mechanism modulates MAVS activity in antiviral innate immune response
por: Shi, Yuheng, et al.
Publicado: (2015) -
Upstream ORFs Prevent MAVS Spontaneous Aggregation and Regulate Innate Immune Homeostasis
por: Shi, Yuheng, et al.
Publicado: (2020) -
Multiple truncated isoforms of MAVS prevent its spontaneous aggregation in antiviral innate immune signalling
por: Qi, Nan, et al.
Publicado: (2017) -
Regulation of MAVS Expression and Signaling Function in the Antiviral Innate Immune Response
por: Ren, Zhihua, et al.
Publicado: (2020) -
Ube2D3 and Ube2N are essential for RIG-I-mediated MAVS aggregation in antiviral innate immunity
por: Shi, Yuheng, et al.
Publicado: (2017)