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CD40 Expressed in Endothelial Cells Promotes Upregulation of ICAM-1 But Not Pro-Inflammatory Cytokines, NOS2 and P2X(7) in the Diabetic Retina

PURPOSE: CD40 is an upstream inducer of inflammation in the diabetic retina. CD40 is upregulated in retinal endothelial cells in diabetes. The purpose of this study was to determine whether expression of CD40 in endothelial cells is sufficient to promote inflammatory responses in the retina of diabe...

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Detalles Bibliográficos
Autores principales: Yu, Jin-Sang, Daw, Jad, Portillo, Jose-Andres C., Subauste, Carlos S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458989/
https://www.ncbi.nlm.nih.gov/pubmed/34546322
http://dx.doi.org/10.1167/iovs.62.12.22