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Akt and its phosphorylation in nucleus accumbens mediate heroin‐seeking behavior induced by cues in rats

Akt is initially identified as one of the downstream targets of phosphatidylinositol‐3 kinase (PI3K) and is involved in morphine reward and tolerance. However, whether phospholyration of Akt (p‐Akt) mediates heroin relapse remains unclear. Here, we aimed to explore the role of p‐Akt in the nucleus a...

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Detalles Bibliográficos
Autores principales: Zhu, Huaqiang, Zhuang, Dingding, Lou, Zhongze, Lai, Miaojun, Fu, Dan, Hong, Qingxiao, Liu, Huifen, Zhou, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459226/
https://www.ncbi.nlm.nih.gov/pubmed/33619816
http://dx.doi.org/10.1111/adb.13013