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Impact of iron raw materials and their impurities on CHO metabolism and recombinant protein product quality

Cell culture medium (CCM) composition affects cell growth and critical quality attributes (CQAs) of monoclonal antibodies (mAbs) and recombinant proteins. One essential compound needed within the medium is iron because of its central role in many cellular processes. However, iron is also participati...

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Detalles Bibliográficos
Autores principales: Weiss, Christine H., Merkel, Corinna, Zimmer, Aline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459231/
https://www.ncbi.nlm.nih.gov/pubmed/33742789
http://dx.doi.org/10.1002/btpr.3148