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Impact of iron raw materials and their impurities on CHO metabolism and recombinant protein product quality
Cell culture medium (CCM) composition affects cell growth and critical quality attributes (CQAs) of monoclonal antibodies (mAbs) and recombinant proteins. One essential compound needed within the medium is iron because of its central role in many cellular processes. However, iron is also participati...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459231/ https://www.ncbi.nlm.nih.gov/pubmed/33742789 http://dx.doi.org/10.1002/btpr.3148 |