Cargando…
Impact of iron raw materials and their impurities on CHO metabolism and recombinant protein product quality
Cell culture medium (CCM) composition affects cell growth and critical quality attributes (CQAs) of monoclonal antibodies (mAbs) and recombinant proteins. One essential compound needed within the medium is iron because of its central role in many cellular processes. However, iron is also participati...
Autores principales: | Weiss, Christine H., Merkel, Corinna, Zimmer, Aline |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459231/ https://www.ncbi.nlm.nih.gov/pubmed/33742789 http://dx.doi.org/10.1002/btpr.3148 |
Ejemplares similares
-
Copper impurity of iron raw material contributes to improved cell culture performance
por: Weiss, Christine Hilde, et al.
Publicado: (2022) -
Spectrofluorimetric determination of selected genotoxic impurities in pharmaceutical raw materials and final products
por: Shallan, Aliaa I., et al.
Publicado: (2022) -
Chemically modified cysteine in CHO fed-batch processes and impact on the specific productivity
por: Hecklau, Caroline, et al.
Publicado: (2015) -
Engineering of CHO cells for the production of vertebrate recombinant sialyltransferases
por: Houeix, Benoit, et al.
Publicado: (2019) -
Impact on product quality of high productive GS-CHO cell lines
por: Perani, Angelo, et al.
Publicado: (2011)