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Angiogenic and immunomodulatory biomarkers in axitinib-treated patients with advanced renal cell carcinoma

AIM: Immunomodulatory mechanisms contributing to angiogenic inhibition in renal tumors are not well characterized. We report associations between efficacy and tumor-associated immune cells and mRNA/miRNA expression in patients from AXIS. MATERIALS & METHODS: Immunohistochemistry (n = 52) and mRN...

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Detalles Bibliográficos
Autores principales: Murphy, Danielle A, Rini, Brian I, Escudier, Bernard, Motzer, Robert J, Wang, Panpan, Li, Sherry, Williams, J Andrew, Tarazi, Jamal C, Martini, Jean-Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459336/
https://www.ncbi.nlm.nih.gov/pubmed/32363929
http://dx.doi.org/10.2217/fon-2020-0212