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Angiogenic and immunomodulatory biomarkers in axitinib-treated patients with advanced renal cell carcinoma
AIM: Immunomodulatory mechanisms contributing to angiogenic inhibition in renal tumors are not well characterized. We report associations between efficacy and tumor-associated immune cells and mRNA/miRNA expression in patients from AXIS. MATERIALS & METHODS: Immunohistochemistry (n = 52) and mRN...
Autores principales: | Murphy, Danielle A, Rini, Brian I, Escudier, Bernard, Motzer, Robert J, Wang, Panpan, Li, Sherry, Williams, J Andrew, Tarazi, Jamal C, Martini, Jean-Francois |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Medicine Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459336/ https://www.ncbi.nlm.nih.gov/pubmed/32363929 http://dx.doi.org/10.2217/fon-2020-0212 |
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