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Weak Binding of Levamisole by the Cocaine-Binding Aptamer Does Not Interfere with an Aptamer-Based Detection Assay

[Image: see text] Levamisole is a common and harmful adulterant of street samples of cocaine and can cause electrochemical tests for cocaine to give false negative results. To see if levamisole would interfere with aptamer-based bioassays, we analyzed the binding of levamisole to the cocaine-binding...

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Detalles Bibliográficos
Autores principales: Shoara, Aron A., Churcher, Zachary R., Slavkovic, Sladjana, Johnson, Philip E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459413/
https://www.ncbi.nlm.nih.gov/pubmed/34568699
http://dx.doi.org/10.1021/acsomega.1c03781