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Response to Sodium Channel blocking Antiseizure medications and coding polymorphisms of Sodium Channel genes in Taiwanese epilepsy patients

BACKGROUND: Many antiseizure medications (ASMs) control seizures by blocking voltage-dependent sodium channels. Polymorphisms of sodium channel genes may affect the response to ASMs due to altering the effect of ASMs on blocking sodium channels. METHODS: We conducted a retrospective study of epileps...

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Detalles Bibliográficos
Autores principales: Lin, Chih-Hsiang, Ho, Chen-Jui, Lu, Yan-Ting, Tsai, Meng-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459515/
https://www.ncbi.nlm.nih.gov/pubmed/34556045
http://dx.doi.org/10.1186/s12883-021-02395-2