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SCReadCounts: estimation of cell-level SNVs expression from scRNA-seq data
BACKGROUND: Recent studies have demonstrated the utility of scRNA-seq SNVs to distinguish tumor from normal cells, characterize intra-tumoral heterogeneity, and define mutation-associated expression signatures. In addition to cancer studies, SNVs from single cells have been useful in studies of tran...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459565/ https://www.ncbi.nlm.nih.gov/pubmed/34551708 http://dx.doi.org/10.1186/s12864-021-07974-8 |