SCReadCounts: estimation of cell-level SNVs expression from scRNA-seq data

BACKGROUND: Recent studies have demonstrated the utility of scRNA-seq SNVs to distinguish tumor from normal cells, characterize intra-tumoral heterogeneity, and define mutation-associated expression signatures. In addition to cancer studies, SNVs from single cells have been useful in studies of tran...

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Detalles Bibliográficos
Autores principales: Prashant, N. M., Alomran, Nawaf, Chen, Yu, Liu, Hongyu, Bousounis, Pavlos, Movassagh, Mercedeh, Edwards, Nathan, Horvath, Anelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459565/
https://www.ncbi.nlm.nih.gov/pubmed/34551708
http://dx.doi.org/10.1186/s12864-021-07974-8

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