SARS-CoV-2 spike protein receptor-binding domain N-glycans facilitate viral internalization in respiratory epithelial cells

N-glycosylation plays an important role in the pathogenesis of viral infections. However, the role of SARS-CoV-2 RBD N-glycosylation in viral entry remains elusive. In this study, we expressed and purified N331 and N343 N-glycosite mutants of SARS-CoV-2 RBD. We found that de-glycosylation at N331 an...

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Detalles Bibliográficos
Autores principales: Zheng, Luping, Ma, Yingxin, Chen, Minghai, Wu, Guoqiang, Yan, Chuang, Zhang, Xian-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459579/
https://www.ncbi.nlm.nih.gov/pubmed/34592572
http://dx.doi.org/10.1016/j.bbrc.2021.09.053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459579/
https://www.ncbi.nlm.nih.gov/pubmed/34592572
http://dx.doi.org/10.1016/j.bbrc.2021.09.053

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