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An engineered probiotic secreting Sj16 ameliorates colitis via Ruminococcaceae/butyrate/retinoic acid axis

Most inflammatory bowel disease (IBD) patients are unable to maintain a lifelong remission. Developing a novel therapeutic strategy is urgently needed. In this study, we adopt a new strategy to attenuate colitis using the Escherichia coli Nissle 1917 probiotic strain to express a schistosome immunor...

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Detalles Bibliográficos
Autores principales: Wang, Lifu, Liao, Yao, Yang, Ruibing, Zhu, Zifeng, Zhang, Lichao, Wu, Zhongdao, Sun, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459592/
https://www.ncbi.nlm.nih.gov/pubmed/34589596
http://dx.doi.org/10.1002/btm2.10219