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Critical Considerations for the Design of Multi-Organ Microphysiological Systems (MPS)

Identification and approval of new drugs for use in patients requires extensive preclinical studies and clinical trials. Preclinical studies rely on in vitro experiments and animal models of human diseases. The transferability of drug toxicity and efficacy estimates to humans from animal models is b...

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Detalles Bibliográficos
Autores principales: Malik, Mridu, Yang, Yang, Fathi, Parinaz, Mahler, Gretchen J., Esch, Mandy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459628/
https://www.ncbi.nlm.nih.gov/pubmed/34568333
http://dx.doi.org/10.3389/fcell.2021.721338