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Human dystrophin expressing chimeric (DEC) cell therapy ameliorates cardiac, respiratory, and skeletal muscle's function in Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a progressive and lethal disease, caused by X‐linked mutations of the dystrophin encoding gene. The lack of dystrophin leads to muscle weakness, degeneration, fibrosis, and progressive loss of skeletal, cardiac, and respiratory muscle function resulting in premat...

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Detalles Bibliográficos
Autores principales: Siemionow, Maria, Langa, Paulina, Harasymczuk, Michal, Cwykiel, Joanna, Sielewicz, Magdalena, Smieszek, Jaroslaw, Heydemann, Ahlke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459641/
https://www.ncbi.nlm.nih.gov/pubmed/34291884
http://dx.doi.org/10.1002/sctm.21-0054