PIK3CA-Related Overgrowth Spectrum From Diagnosis to Targeted Therapy: A Case of CLOVES Syndrome Treated With Alpelisib

PIK3CA-related overgrowth spectrum (PROS) is an umbrella term referring to various clinical entities, which share the same pathogenetic mechanism. These conditions are caused by somatic gain-of-function mutations in PIK3CA, which encodes the 110-kD catalytic α subunit of PI3K (p110α). These PIK3CA m...

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Detalles Bibliográficos
Autores principales: Pagliazzi, Angelica, Oranges, Teresa, Traficante, Giovanna, Trapani, Chiara, Facchini, Flavio, Martin, Alessandra, Semeraro, Alessandro, Perrone, Anna, Filippeschi, Cesare, Giglio, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459713/
https://www.ncbi.nlm.nih.gov/pubmed/34568242
http://dx.doi.org/10.3389/fped.2021.732836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459713/
https://www.ncbi.nlm.nih.gov/pubmed/34568242
http://dx.doi.org/10.3389/fped.2021.732836

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