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The structural basis of Salmonella A(2)B(5) toxin neutralization by antibodies targeting the glycan-receptor binding subunits

Many bacterial pathogens secrete A((2))B(5) toxins comprising two functionally distinct yet complementary “A” and “B” subunits to benefit the pathogens during infection. The lectin-like pentameric B subunits recognize specific sets of host glycans to deliver the toxin into target host cells. Here, w...

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Detalles Bibliográficos
Autores principales: Nguyen, Tri, Richards, Angelene F., Neupane, Durga P., Feathers, J. Ryan, Yang, Yi-An, Sim, Ji Hyun, Byun, Haewon, Lee, Sohyoung, Ahn, Changhwan, Van Slyke, Greta, Fromme, J. Christopher, Mantis, Nicholas J., Song, Jeongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459933/
https://www.ncbi.nlm.nih.gov/pubmed/34496256
http://dx.doi.org/10.1016/j.celrep.2021.109654