Cargando…
The structural basis of Salmonella A(2)B(5) toxin neutralization by antibodies targeting the glycan-receptor binding subunits
Many bacterial pathogens secrete A((2))B(5) toxins comprising two functionally distinct yet complementary “A” and “B” subunits to benefit the pathogens during infection. The lectin-like pentameric B subunits recognize specific sets of host glycans to deliver the toxin into target host cells. Here, w...
Autores principales: | Nguyen, Tri, Richards, Angelene F., Neupane, Durga P., Feathers, J. Ryan, Yang, Yi-An, Sim, Ji Hyun, Byun, Haewon, Lee, Sohyoung, Ahn, Changhwan, Van Slyke, Greta, Fromme, J. Christopher, Mantis, Nicholas J., Song, Jeongmin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459933/ https://www.ncbi.nlm.nih.gov/pubmed/34496256 http://dx.doi.org/10.1016/j.celrep.2021.109654 |
Ejemplares similares
-
Mechanisms of typhoid toxin neutralization by antibodies targeting glycan receptor binding and nuclease subunits
por: Ahn, Changhwan, et al.
Publicado: (2021) -
The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication
por: Nguyen, Tri, et al.
Publicado: (2020) -
The Role of Typhoid Toxin in Salmonella Typhi Virulence
por: Chong, Alexander, et al.
Publicado: (2017) -
Neutralization of Typhoid Toxin by Alpaca-Derived, Single-Domain Antibodies Targeting the PltB and CdtB Subunits
por: Dulal, Hari P., et al.
Publicado: (2022) -
Spatial location of neutralizing and non-neutralizing B cell epitopes on domain 1 of ricin toxin’s binding subunit
por: Rong, Yinghui, et al.
Publicado: (2017)