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TRIM25 inhibits infectious bursal disease virus replication by targeting VP3 for ubiquitination and degradation

Infectious bursal disease virus (IBDV), a double-stranded RNA virus, causes immunosuppression and high mortality in 3–6-week-old chickens. Innate immune defense is a physical barrier to restrict viral replication. After viral infection, the host shows crucial defense responses, such as stimulation o...

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Detalles Bibliográficos
Autores principales: Wang, Suyan, Yu, Mengmeng, Liu, Aijing, Bao, Yuanling, Qi, Xiaole, Gao, Li, Chen, Yuntong, Liu, Peng, Wang, Yulong, Xing, Lixiao, Meng, Lingzhai, Zhang, Yu, Fan, Linjin, Li, Xinyi, Pan, Qing, Zhang, Yanping, Cui, Hongyu, Li, Kai, Liu, Changjun, He, Xijun, Gao, Yulong, Wang, Xiaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459960/
https://www.ncbi.nlm.nih.gov/pubmed/34516573
http://dx.doi.org/10.1371/journal.ppat.1009900